Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.48 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 2/20 | 0.45 |
| ▸ | HRAS | P01112 | 1/20 | 0.45 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13046082 | 0.91 | LMNA (0.60) | LMNAP2RX3P2RX4P2RX2MEN1 | |
| SCHEMBL13046077 | 0.91 | LMNA (0.60) | LMNAP2RX3P2RX4P2RX2MEN1 | |
| SCHEMBL13046087 | 0.91 | LMNA (0.60) | LMNAP2RX3P2RX4P2RX2MEN1 | |
| SCHEMBL13864334 | 0.90 | LMNA (0.56) | LMNAP2RX3P2RX4P2RX2MEN1 | |
| SCHEMBL13046095 | 0.88 | LMNA (0.75) | LMNAP2RX3P2RX4P2RX2MEN1 | |
| SCHEMBL14075778 | 0.88 | LMNA (0.75) | LMNAP2RX3P2RX4P2RX2MEN1 | |
| SCHEMBL13084357 | 0.88 | LMNA (0.75) | LMNAP2RX3P2RX4P2RX2MEN1 | |
| SCHEMBL13863569 | 0.88 | LMNA (0.75) | LMNAP2RX3P2RX4P2RX2MEN1 | |
| SCHEMBL13863571 | 0.88 | LMNA (0.55) | LMNAP2RX3P2RX4P2RX2MEN1 | |
| SCHEMBL14075777 | 0.88 | LMNA (0.55) | LMNAP2RX3P2RX4P2RX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140212916-A1 | RAPID TEST FOR DETECTION OF INFECTION AND THERAPEUTIC RESPONSE | STC.UNM | 2014-07-31 | — | — | US | disclosed |
| WO-2009087066-A2 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2009-07-16 | — | — | WO | disclosed |