Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.40 |
| ▸ | CNR2 | P34972 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770196 | 0.86 | MAPT (0.44) | CNR1CNR2MAPTTP53POLB | |
| SCHEMBL13769533 | 0.86 | MAPT (0.44) | CNR1CNR2MAPTTP53POLB | |
| SCHEMBL13769679 | 0.84 | CNR1 (0.49) | CNR1CNR2MAPTTP53POLB | |
| SCHEMBL13770135 | 0.82 | MAPT (0.47) | CNR1CNR2MAPTTP53POLB | |
| SCHEMBL4006144 | 0.79 | KMT2A (0.46) | CNR1CNR2MAPTTP53POLB | |
| SCHEMBL4006140 | 0.78 | CNR1 (0.56) | CNR1CNR2MAPTTP53POLB | |
| SCHEMBL13769532 | 0.77 | PDE4B (0.41) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL13769975 | 0.76 | CNR1 (0.34) | CNR1CNR2 | |
| SCHEMBL13769525 | 0.76 | MAPT (0.40) | CNR1CNR2MAPTTP53KDM4E | |
| SCHEMBL13769677 | 0.75 | MAPT (0.38) | MAPTTP53KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080682-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |