Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.60 |
| ▸ | SOAT1 | P35610 | 13/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5578312 | 0.84 | DGAT1 (0.57) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2255367 | 0.75 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL5532585 | 0.71 | DGAT1 (0.72) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL5532372 | 0.70 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL23339907 | 0.70 | DGAT1 (0.67) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL12377450 | 0.69 | DGAT1 (0.56) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2126247 | 0.69 | DGAT1 (0.65) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL5533599 | 0.69 | DGAT1 (0.76) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2254137 | 0.69 | DGAT1 (0.68) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2253827 | 0.68 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081195-A1 | CARBAMOYL COMPOUNDS AS DGAT1 INHIBITORS 190 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |