Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.43 |
| ▸ | PGR | P06401 | 15/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13474755 | 0.83 | AR (0.61) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13770138 | 0.81 | AR (0.62) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13770151 | 0.80 | PGR (0.59) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13474748 | 0.78 | AR (0.60) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13770153 | 0.78 | AR (0.59) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13770134 | 0.78 | AR (0.60) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13769022 | 0.75 | PGR (0.42) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13770654 | 0.70 | PGR (0.61) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13770462 | 0.69 | PGR (0.57) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13474783 | 0.69 | PGR (0.57) | ARPGRNR3C2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083268-A2 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |