Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | AR | P10275 | 5/20 | 0.55 |
| ▸ | ESR1 | P03372 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | SHBG | P04278 | 4/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25868093 | 0.86 | PGR (0.73) | PGRSLC6A4LMNAARESR1 | |
| SCHEMBL25867708 | 0.86 | PGR (0.73) | PGRSLC6A4LMNAARESR1 | |
| SCHEMBL11861988 | 0.86 | PGR (0.73) | PGRSLC6A4LMNAARESR1 | |
| SCHEMBL14255119 | 0.84 | PGR (0.77) | PGRSLC6A4LMNAARESR1 | |
| SCHEMBL22382702 | 0.84 | NR1I2 (0.74) | PGRSLC6A4LMNAARESR1 | |
| SCHEMBL13062175 | 0.79 | PGR (0.50) | PGRSLC6A4LMNAARESR1 | |
| SCHEMBL16715966 | 0.78 | AR (0.80) | PGRSLC6A4LMNAARESR1 | |
| SCHEMBL11861950 | 0.77 | CYP3A4 (0.64) | PGRSLC6A4LMNAARESR1 | |
| SCHEMBL12923998 | 0.77 | PGR (0.82) | PGRSLC6A4LMNAARESR1 | |
| Norbolethone SCHEMBL548124 | 0.74 | PGR (0.73) | PGRSLC6A4LMNAARESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083267-A2 | STEROID-17,17-LACTOL DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |