Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.48 |
| ▸ | ADK | P55263 | 10/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12151837 | 0.91 | ADORA2A (0.65) | ADORA2APRMT5WDR77ADKADORA3 | |
| SCHEMBL12149498 | 0.91 | ADORA2A (0.65) | ADORA2APRMT5WDR77ADKADORA3 | |
| SCHEMBL16174352 | 0.91 | ADORA2A (0.65) | ADORA2APRMT5WDR77ADKADORA3 | |
| SCHEMBL12758164 | 0.91 | ADORA2A (0.65) | ADORA2APRMT5WDR77ADKADORA3 | |
| SCHEMBL731182 | 0.91 | ADORA2A (0.65) | ADORA2APRMT5WDR77ADKADORA3 | |
| SCHEMBL24837545 | 0.91 | ADORA2A (0.65) | ADORA2APRMT5WDR77ADKADORA3 | |
| SCHEMBL15759356 | 0.91 | ADORA2A (0.65) | ADORA2APRMT5WDR77ADKADORA3 | |
| SCHEMBL18636317 | 0.91 | ADORA2A (0.65) | ADORA2APRMT5WDR77ADKADORA3 | |
| SCHEMBL19402612 | 0.85 | PRMT5 (0.48) | ADORA2APRMT5WDR77ADKADORA3 | |
| SCHEMBL15960575 | 0.82 | PRMT5 (0.48) | ADORA2APRMT5WDR77ADKADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086201-A1 | 2-5A ANALOGS AND THEIR USE AS ANTI-CANCER, ANTI-VIRAL AND ANTI- PARAS ITI C AGENTS | ALIOS BIOPHARMA, INC. (US) | 2009-07-09 | — | — | WO | disclosed |