Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.49 |
| ▸ | PGR | P06401 | 14/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769109 | 0.79 | AR (0.47) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL13770653 | 0.77 | AR (0.48) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL13770649 | 0.76 | AR (0.44) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL13770651 | 0.74 | PGR (0.49) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL5973825 | 0.72 | CYP19A1 (0.62) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL1656778 | 0.72 | CYP19A1 (0.62) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL24102603 | 0.72 | AR (0.74) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL6841921 | 0.72 | AR (0.74) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL6241583 | 0.72 | AR (0.74) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL24102607 | 0.72 | AR (0.74) | ARPGRNR3C2SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083268-A2 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |