Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.59 |
| ▸ | PGR | P06401 | 10/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.47 |
| ▸ | SHBG | P04278 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13397510 | 1.00 | AR (0.59) | ARNR3C2PGRSERPINA6SHBG | |
| SCHEMBL13770159 | 1.00 | AR (0.59) | ARNR3C2PGRSERPINA6SHBG | |
| SCHEMBL5026470 | 0.88 | AR (0.72) | ARNR3C2PGRSERPINA6SHBG | |
| SCHEMBL17302821 | 0.88 | AR (0.72) | ARNR3C2PGRSERPINA6SHBG | |
| SCHEMBL13334513 | 0.85 | AR (0.58) | ARNR3C2PGRSERPINA6SHBG | |
| SCHEMBL4211987 | 0.85 | AR (0.58) | ARNR3C2PGRSERPINA6SHBG | |
| SCHEMBL6464435 | 0.85 | AR (0.55) | ARNR3C2PGRSERPINA6SHBG | |
| SCHEMBL4215694 | 0.85 | AR (0.58) | ARNR3C2PGRSERPINA6SHBG | |
| SCHEMBL12884315 | 0.85 | AR (0.78) | ARNR3C2PGRSERPINA6SHBG | |
| SCHEMBL25863881 | 0.85 | AR (0.78) | ARNR3C2PGRSERPINA6SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083268-A2 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |