Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.55 |
| ▸ | PGR | P06401 | 9/20 | 0.55 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17302821 | 0.86 | AR (0.72) | ARNR3C2PGRSERPINA6SLC22A1 | |
| SCHEMBL5026470 | 0.86 | AR (0.72) | ARNR3C2PGRSERPINA6SLC22A1 | |
| SCHEMBL13397510 | 0.85 | AR (0.59) | ARNR3C2PGRSERPINA6SLC22A1 | |
| SCHEMBL13770159 | 0.85 | AR (0.59) | ARNR3C2PGRSERPINA6SLC22A1 | |
| SCHEMBL13770461 | 0.85 | AR (0.59) | ARNR3C2PGRSERPINA6SLC22A1 | |
| SCHEMBL6462161 | 0.85 | AR (0.74) | ARNR3C2PGRSERPINA6SLC22A1 | |
| SCHEMBL6464786 | 0.83 | AR (0.56) | ARNR3C2PGRSERPINA6SLC22A1 | |
| SCHEMBL4211987 | 0.82 | AR (0.58) | ARNR3C2PGRSERPINA6SLC22A1 | |
| SCHEMBL4215694 | 0.82 | AR (0.58) | ARNR3C2PGRSERPINA6SLC22A1 | |
| SCHEMBL13334513 | 0.82 | AR (0.58) | ARNR3C2PGRSERPINA6SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881728-B1 | 14-β, 17-α-hydroxymethylandrostane derivatives as androgens | AKZO NOBEL N.V. (NL) | 2005-04-19 | — | — | US | disclosed |
| EP-1163259-B1 | 14.BETA.,17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | AKZO NOBEL NV (NL) | 2002-11-20 | — | — | EP | disclosed |