Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.67 |
| ▸ | PGR | P06401 | 14/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062181 | 1.00 | AR (0.67) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13062443 | 0.89 | AR (0.68) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13062183 | 0.89 | AR (0.68) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13062199 | 0.88 | AR (0.52) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13062201 | 0.87 | AR (0.69) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL12949519 | 0.85 | AR (0.67) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13062434 | 0.85 | AR (0.66) | ARPGRNR3C2SHBG | |
| SCHEMBL13062191 | 0.85 | PGR (0.66) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13062455 | 0.82 | AR (0.47) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13062461 | 0.82 | AR (0.47) | ARPGRNR3C2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083268-A2 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |