Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770335 | 0.88 | NOX1 (0.43) | NQO2MAPTMEN1NPC1POLB | |
| SCHEMBL13770447 | 0.85 | NOX1 (0.60) | NQO2MAPTMEN1NPC1POLB | |
| SCHEMBL31315040 | 0.85 | NOX1 (0.60) | NQO2MAPTMEN1NPC1POLB | |
| SCHEMBL13770622 | 0.82 | CHEK1 (0.51) | NQO2MAPTMEN1NPC1POLB | |
| SCHEMBL8686412 | 0.82 | NQO2 (0.62) | NQO2MAPTMEN1NPC1POLB | |
| SCHEMBL13770441 | 0.79 | CHEK1 (0.47) | NQO2MAPTMEN1KMT2AUSP2 | |
| SCHEMBL17049807 | 0.78 | NOX1 (0.47) | NQO2MAPTMEN1NPC1POLB | |
| SCHEMBL4612924 | 0.71 | MAPT (0.79) | NQO2MAPTMEN1NPC1POLB | |
| SCHEMBL13156546 | 0.71 | MAPT (0.79) | NQO2MAPTMEN1NPC1POLB | |
| SCHEMBL29614768 | 0.71 | MAPT (0.79) | NQO2MAPTMEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078720-A1 | Novel method for the preparation of derivatives of dihydrotetraazapentacenes, products such as obtained and uses thereof | Université de la Méditerranée - Aix-Marseille II (FR) | 2009-07-15 | — | — | EP | disclosed |
| WO-2009083532-A2 | NOVEL METHOD FOR THE PREPARATION OF DERIVATIVES OF DIHYDROTETRAAZAPENTACENES, PRODUCTS SUCH AS OBTAINED, AND USES THEREOF | UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) | 2009-07-09 | — | — | WO | disclosed |