SCHEMBL13156546

SCHEMBL13156546

c1ccc2nc3cc4nc5cc6nc7ccccc7nc6cc5nc4cc3nc2c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.79
NQO2 P16083 7/20 0.77
KMT2A Q03164 4/20 0.68
MEN1 O00255 3/20 0.68
NPC1 O15118 3/20 0.68
POLB P06746 2/20 0.68
USP2 O75604 1/20 0.68
CACNA1B Q00975 1/20 0.68
APBA1 Q02410 1/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
ALDH1A1 P00352 5/20 0.61
HPGD P15428 3/20 0.61
GLA P06280 2/20 0.61
ACHE P22303 2/20 0.61
KDM4E B2RXH2 4/20 0.54
RAB9A P51151 4/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
LMNA P02545 1/20 0.54
GAA P10253 2/20 0.53
HSD17B10 Q99714 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29614768 1.00 MAPT (0.79) MAPTNQO2KMT2AMEN1NPC1
SCHEMBL4612924 1.00 MAPT (0.79) MAPTNQO2KMT2AMEN1NPC1
SCHEMBL31319857 0.91 NQO2 (0.94) MAPTNQO2KMT2AMEN1NPC1
Phenazine SCHEMBL9049 0.89 MAPT (1.00) MAPTNQO2KMT2AMEN1NPC1
Phenazine SCHEMBL29356959 0.89 MAPT (1.00) MAPTNQO2KMT2AMEN1NPC1
Phenazine SCHEMBL27643128 0.89 MAPT (1.00) MAPTNQO2KMT2AMEN1NPC1
Benzo[B]Phenazine SCHEMBL5481172 0.87 NQO2 (1.00) MAPTNQO2KMT2AMEN1NPC1
SCHEMBL13156530 0.86 NQO2 (0.59) MAPTNQO2KMT2AMEN1NPC1
SCHEMBL31315039 0.86 NQO2 (0.59) MAPTNQO2KMT2AMEN1NPC1
SCHEMBL17652916 0.86 NQO2 (0.68) MAPTNQO2KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7800103-B2 Organic thin film transistor material, organic thin film transistor, field-effect transistor, switching element, organic semiconductor material and organic semiconductor film KONICA MINOLTA HOLDINGS, INC. (JP) 2010-09-21 US disclosed
US-7800103-B2 Organic thin film transistor material, organic thin film transistor, field-effect transistor, switching element, organic semiconductor material and organic semiconductor film KONICA MINOLTA HOLDINGS, INC. (JP) 2010-09-21 US disclosed
US-20080121873-A1 Organic Thin Film Transistor Material, Organic Thin Film Transistor, Field-Effect Transistor, Switching Element, Organic Semiconductor Material and Organic Semiconductor Film KONICA MINOLTA HOLDINGS, INC. (JP) 2008-05-29 US disclosed
US-20080121873-A1 Organic Thin Film Transistor Material, Organic Thin Film Transistor, Field-Effect Transistor, Switching Element, Organic Semiconductor Material and Organic Semiconductor Film KONICA MINOLTA HOLDINGS, INC. (JP) 2008-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080121873-A1 Organic Thin Film Transistor Material, Organic Thin Film Transistor, Field-Effect Transistor, Switching Element, Organic Semiconductor Material and Organic Semiconductor Film TERT, TELO2, RCOR1 MAPT 433/4885NQO2 2650/4885KMT2A 1347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.