Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13771407 | 0.89 | METTL3 (0.30) | METTL3 | |
| SCHEMBL13771387 | 0.89 | METTL3 (0.53) | METTL3PTPN1KLKB1CFDTSHR | |
| SCHEMBL13771366 | 0.88 | METTL3 (0.45) | METTL3PTPN1CFDCD38 | |
| SCHEMBL11956108 | 0.85 | METTL3 (0.44) | METTL3PTPN1KLKB1CFD | |
| SCHEMBL12413342 | 0.84 | METTL3 (0.42) | METTL3PTPN1CXCR2CFDPCSK9 | |
| SCHEMBL12107664 | 0.83 | METTL3 (0.42) | METTL3PTPN1 | |
| SCHEMBL12107653 | 0.83 | METTL3 (0.46) | METTL3PTPN1CFDPCSK9CD38 | |
| SCHEMBL12107671 | 0.82 | METTL3 (0.41) | METTL3PTPN1CFDPCSK9CD38 | |
| SCHEMBL11956959 | 0.82 | METTL3 (0.41) | METTL3PTPN1 | |
| SCHEMBL12107665 | 0.82 | METTL3 (0.41) | METTL3PTPN1PCSK9CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089263-A2 | NOVEL COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES INC. (US) | 2009-07-16 | — | — | WO | disclosed |