Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 14/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284689 | 0.87 | CA12 (0.39) | KDM4EHPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL8284613 | 0.85 | KDM4E (0.41) | KDM4EHPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL8284698 | 0.83 | CDK1 (0.42) | KDM4EHPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL8284693 | 0.82 | KDM4E (0.37) | KDM4EHPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL8284692 | 0.82 | KDM4E (0.44) | KDM4EHPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL8284700 | 0.73 | CA12 (0.45) | KDM4EALDH1A1 | |
| SCHEMBL2536267 | 0.73 | MAPT (0.41) | KDM4EHPGDALDH1A1 | |
| SCHEMBL13932114 | 0.72 | KDM4E (0.43) | KDM4EHPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL8284696 | 0.71 | SIRT2 (0.48) | KDM4EHPGDALDH1A1 | |
| SCHEMBL8284602 | 0.70 | KDM4E (0.38) | KDM4EHPGDUSP2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697343-B1 | AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARM LTD (IE) | 2009-07-01 | — | — | EP | disclosed |