Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 9/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284613 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1HPGDL3MBTL1USP2 | |
| SCHEMBL14003034 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1HPGDUSP2HSD17B10 | |
| SCHEMBL8283679 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1HPGDUSP2HSD17B10 | |
| SCHEMBL8284750 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1HPGDUSP2HSD17B10 | |
| SCHEMBL4284545 | 0.80 | KDM4E (0.37) | KDM4EALDH1A1HPGDL3MBTL1USP2 | |
| SCHEMBL4281670 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1HPGDUSP2HSD17B10 | |
| SCHEMBL8288282 | 0.78 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDL3MBTL1USP2 | |
| SCHEMBL8285627 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1HPGDUSP2HSD17B10 | |
| SCHEMBL4280686 | 0.77 | P2RX3 (0.34) | KDM4EALDH1A1GFER | |
| SCHEMBL8285106 | 0.77 | SOS1 (0.45) | KDM4EALDH1A1HPGDUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | BONFANTI JEAN-FRANCOIS | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | NQO2, NOX3, NOX1 | KDM4E 3254/4885ALDH1A1 2090/4885HPGD 1978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.