Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14179076 | 0.88 | THRB (0.63) | THRBTHRAMEN1ALDH1A1CYP3A4 | |
| SCHEMBL15854397 | 0.84 | THRB (0.38) | THRBFFAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13777561 | 0.84 | THRB (0.50) | THRBFFAR1ALDH1A1LMNACYP3A4 | |
| SCHEMBL2602538 | 0.81 | THRB (0.56) | THRBTHRAMEN1ALDH1A1LMNA | |
| SCHEMBL14179080 | 0.81 | THRB (0.40) | THRBFFAR1MEN1ALDH1A1MAPK1 | |
| SCHEMBL13777614 | 0.81 | MEN1 (0.43) | THRBPLA2G4BMEN1ALDH1A1CYP3A4 | |
| SCHEMBL13777562 | 0.81 | MAPT (0.47) | THRBMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL13777566 | 0.80 | THRB (0.40) | THRBMEN1ALDH1A1LMNAMAPK1 | |
| SCHEMBL13777552 | 0.80 | MAPT (0.46) | THRBPLA2G4B | |
| SCHEMBL14436738 | 0.77 | THRB (0.40) | THRBPLA2G4BALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563553-B2 | Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2009-07-21 | — | — | US | disclosed |
| US-20070178400-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2007-08-02 | — | — | US | disclosed |