Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | ESRRG | P62508 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13778182 | 0.85 | NR1H4 (0.54) | MMP12MMP13SLC13A5NR1H4EPHX2 | |
| SCHEMBL13778155 | 0.83 | HTT (0.56) | SMN1; SMN2SLC13A5NR1H4EPHX2LMNA | |
| SCHEMBL13870214 | 0.81 | MMP12 (0.67) | MMP12MMP13SMN1; SMN2TSHRCES1 | |
| SCHEMBL4574068 | 0.80 | MMP12 (0.82) | MMP12MMP13SMN1; SMN2TSHRCES1 | |
| SCHEMBL13273688 | 0.79 | MMP12 (0.69) | MMP12MMP13SMN1; SMN2TSHRCES1 | |
| SCHEMBL846131 | 0.77 | NR1H4 (0.71) | SLC13A5NR1H4EPHX2ESRRGRXRA | |
| SCHEMBL13778147 | 0.76 | CYP2C19 (0.56) | SMN1; SMN2CES1ESRRGRAB9ANPC1 | |
| SCHEMBL5069416 | 0.75 | MMP12 (0.64) | MMP12MMP13SMN1; SMN2TSHRCES1 | |
| SCHEMBL1453852 | 0.74 | NR1H4 (0.73) | SMN1; SMN2TSHRSLC13A5NR1H4EPHX2 | |
| SCHEMBL13778164 | 0.73 | CYP2C19 (0.64) | SMN1; SMN2SLC13A5NR1H4EPHX2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170911-A1 | NOVEL AZOLE COMPOUND | AJINOMOTO CO. INC (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090170911-A1 | NOVEL AZOLE COMPOUND | AJINOMOTO CO. INC (JP) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170911-A1 | NOVEL AZOLE COMPOUND | LPAR1, LPAR2, LPAR3 | MMP12 3504/4885MMP13 4094/4885SMN1; SMN2 4589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.