Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15161688 | 0.91 | HRH3 (0.65) | HRH3KCNH2RORCPYCR1MAPT | |
| SCHEMBL20287494 | 0.91 | HRH3 (0.72) | HRH3KCNH2RORCPYCR1MAPT | |
| SCHEMBL12203962 | 0.88 | KCNH2 (0.61) | HRH3KCNH2MAPT | |
| SCHEMBL5925786 | 0.87 | HRH3 (0.70) | HRH3KCNH2PYCR1 | |
| SCHEMBL12763728 | 0.87 | HRH3 (0.62) | HRH3KCNH2PYCR1 | |
| SCHEMBL24061143 | 0.86 | HRH3 (0.84) | HRH3KCNH2RORCPYCR1MAPT | |
| SCHEMBL8252162 | 0.85 | HRH3 (0.63) | HRH3RORCPYCR1MAPT | |
| Water SCHEMBL9810829 | 0.85 | HRH3 (0.67) | HRH3KCNH2PYCR1 | |
| SCHEMBL12679260 | 0.84 | HRH3 (0.50) | HRH3KCNH2 | |
| SCHEMBL17468352 | 0.82 | HRH3 (0.60) | HRH3KCNH2RORCPYCR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192182-A1 | COMPOUND HAVING ACIDIC GROUP WHICH MAY BE PROTECTED, AND USE THEREOF | ONO PHARMACEUTICAL CO.,LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192182-A1 | COMPOUND HAVING ACIDIC GROUP WHICH MAY BE PROTECTED, AND USE THEREOF | CXCR4, CXCR3, CXCL12 | HRH3 266/4885KCNH2 4343/4885RORC 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.