Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1658381 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CYP3A4ALOX15CYP2C19 | |
| SCHEMBL1658382 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CYP3A4ALOX15CYP2C19 | |
| SCHEMBL13778585 | 0.71 | — | — | |
| SCHEMBL14226006 | 0.69 | — | — | |
| SCHEMBL12552285 | 0.69 | — | — | |
| SCHEMBL15934502 | 0.69 | — | — | |
| SCHEMBL15934506 | 0.69 | — | — | |
| SCHEMBL15934510 | 0.69 | — | — | |
| SCHEMBL14701160 | 0.69 | — | — | |
| SCHEMBL5837629 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160297790-A1 | CYTOTOXIN COMPOUNDS AND METHODS OF ISOLATION | UNIV SOUTH FLORIDA (US) | 2016-10-13 | — | — | US | disclosed |
| US-9394270-B2 | Cytotoxin compounds and methods of isolation | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-07-19 | — | — | US | disclosed |
| US-20140194495-A1 | CYTOTOXIN COMPOUNDS AND METHODS OF ISOLATION | THE UAB RESEARCH FOUNDATION (US) | 2014-07-10 | — | — | US | disclosed |
| US-8669376-B2 | Cytotoxin compounds and methods of isolation | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-03-11 | — | — | US | disclosed |
| US-20090192215-A1 | Cytotoxin Compounds and Methods of Isolation | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194495-A1 | CYTOTOXIN COMPOUNDS AND METHODS OF ISOLATION | XPA, ANXA5, ST14 | ALDH1A1 4056/4885CYP3A4 4730/4885ALOX15 1922/4885 |
| US-20090192215-A1 | Cytotoxin Compounds and Methods of Isolation | XPA, ANXA5, ST14 | ALDH1A1 4056/4885CYP3A4 4730/4885ALOX15 1922/4885 |
| US-20160297790-A1 | CYTOTOXIN COMPOUNDS AND METHODS OF ISOLATION | XPA, ANXA5, ST14 | ALDH1A1 4056/4885CYP3A4 4730/4885ALOX15 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.