Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13778798 | 0.89 | RXFP1 (0.39) | CNR1CNR2BRD4MAPTPRNP | |
| SCHEMBL13778788 | 0.89 | CNR1 (0.39) | CNR1CNR2BRD4RXFP1FSCN1 | |
| SCHEMBL4160989 | 0.82 | MEN1 (0.41) | CNR1CNR2MAPTPRNPFSCN1 | |
| SCHEMBL1684180 | 0.78 | MEN1 (0.40) | MAPTPRNPFSCN1POLBMEN1 | |
| SCHEMBL4170043 | 0.75 | CHRM1 (0.50) | RXFP1POLB | |
| SCHEMBL13778809 | 0.73 | CNR2 (0.48) | CNR2 | |
| SCHEMBL13778787 | 0.73 | FSCN1 (0.39) | MAPTPRNPFSCN1MEN1KMT2A | |
| SCHEMBL4165466 | 0.72 | PDE4A (0.38) | MAPTPRNPPOLBMEN1KMT2A | |
| SCHEMBL5520368 | 0.72 | CACNB4 (0.46) | MAPTRXFP1 | |
| SCHEMBL4798568 | 0.72 | THRB (0.39) | MAPTPRNPPOLBGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170846-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER INC | 2009-07-02 | — | — | US | disclosed |
| US-20090170846-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER INC | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170846-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | IMPDH1, IMPA1, TYMP | CNR1 4750/4885CNR2 4856/4885BRD4 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.