SCHEMBL13778807

SCHEMBL13778807

CCN(CC)c1ccc(C(c2ccc(N(CC)CC)cc2)(c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ MAPK1 P28482 2/20 0.45
▸ PSMD14 O00487 1/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ RECQL P46063 1/20 0.45
▸ GFER P55789 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ CNR2 P34972 13/20 0.44
▸ CNR1 P21554 9/20 0.43
▸ ALDH3A1 P30838 1/20 0.42
▸ ALDH1A3 P47895 1/20 0.42
▸ MAPT P10636 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ CYP2C19 P33261 1/20 0.40
▸ S100B P04271 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13778814 1.00 TSHR (0.45) TSHRALDH1A1MAPK1PSMD14CYP3A4
SCHEMBL13778811 0.95 TSHR (0.41) TSHRALDH1A1MAPK1PSMD14CYP3A4
SCHEMBL13778810 0.95 TSHR (0.41) TSHRALDH1A1MAPK1PSMD14CYP3A4
SCHEMBL13778797 0.95 TSHR (0.41) TSHRALDH1A1MAPK1PSMD14CYP3A4
SCHEMBL13778816 0.95 TSHR (0.41) TSHRALDH1A1MAPK1PSMD14CYP3A4
SCHEMBL13778795 0.93 CYP2C19 (0.47) TSHRALDH1A1MAPK1PSMD14CYP3A4
SCHEMBL12342193 0.89 CYP2C19 (0.50) TSHRALDH1A1MAPK1PSMD14CYP3A4
SCHEMBL13211689 0.88 ALDH1A1 (0.56) TSHRALDH1A1MAPK1PSMD14CYP3A4
SCHEMBL6754809 0.88 TSHR (0.52) TSHRALDH1A1TDP1MAPTCYP2C19
SCHEMBL13778819 0.84 CYP2C19 (0.46) TSHRCNR2CNR1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 — — US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 — — US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 — — US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 — — US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 — — US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 — — US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 — — US disclosed
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