SCHEMBL13778817

SCHEMBL13778817

CCOc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C(c4ccc(N(CC)CC)cc4)(c4ccc(N(c5ccc(C)cc5)c5ccc(-c6ccc(OCC)cc6)cc5)cc4)c4ccc(N(c5ccc(C)cc5)c5ccc(-c6ccc(OCC)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.46
▸ MAPK1 P28482 2/20 0.46
▸ HTT P42858 2/20 0.46
▸ TSHR P16473 2/20 0.46
▸ POLB P06746 2/20 0.43
▸ CACNA2D1 P54289 1/20 0.38
▸ NQO1 P15559 1/20 0.38
▸ CNR2 P34972 2/20 0.37
▸ CNR1 P21554 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ KMT2A Q03164 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13778862 0.90 MAPT (0.41) MAPTMAPK1HTTTSHRPOLB
SCHEMBL13778810 0.89 TSHR (0.41) MAPTMAPK1HTTTSHRCNR2
SCHEMBL13778816 0.89 TSHR (0.41) MAPTMAPK1HTTTSHRCNR2
SCHEMBL13778797 0.89 TSHR (0.41) MAPTMAPK1HTTTSHRCNR2
SCHEMBL13778811 0.89 TSHR (0.41) MAPTMAPK1HTTTSHRCNR2
SCHEMBL13778814 0.84 TSHR (0.45) MAPTMAPK1HTTTSHRCNR2
SCHEMBL13778807 0.84 TSHR (0.45) MAPTMAPK1HTTTSHRCNR2
SCHEMBL12680650 0.84 NQO1 (0.54) MAPTTSHRCACNA2D1NQO1CNR2
SCHEMBL19607554 0.84 NQO1 (0.54) MAPTTSHRCACNA2D1NQO1CNR2
SCHEMBL13778819 0.79 CYP2C19 (0.46) TSHRCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 — — US disclosed
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 — — US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 — — US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 — — US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 — — US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 — — US disclosed
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