Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.55 |
| ▸ | BCR | P11274 | 15/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.55 |
| ▸ | KIT | P10721 | 2/20 | 0.55 |
| ▸ | LYN | P07948 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | YES1 | P07947 | 1/20 | 0.55 |
| ▸ | HCK | P08631 | 1/20 | 0.55 |
| ▸ | FGR | P09769 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | SLC25A6 | P12236 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377910 | 0.94 | ABL1 (0.54) | ABL1BCRPDGFRBKITLYN | |
| SCHEMBL716373 | 0.91 | ABL1 (0.63) | ABL1BCRPDGFRBKITLYN | |
| SCHEMBL5489182 | 0.87 | ABL1 (0.44) | ABL1BCRPDGFRBKITLYN | |
| SCHEMBL5091638 | 0.85 | ABL1 (0.44) | ABL1BCRPDGFRBKITLYN | |
| SCHEMBL6287781 | 0.79 | ABL1 (0.60) | ABL1BCRPDGFRBKITLYN | |
| SCHEMBL716387 | 0.78 | ABL1 (0.63) | ABL1BCRPDGFRBKITLYN | |
| SCHEMBL715940 | 0.77 | ABL1 (0.85) | ABL1BCRPDGFRBKITLYN | |
| SCHEMBL4825391 | 0.76 | ABL1 (0.66) | ABL1BCRPDGFRBKITLYN | |
| SCHEMBL5176285 | 0.75 | ABL1 (0.49) | ABL1BCRPDGFRBKITLYN | |
| SCHEMBL4902752 | 0.75 | ALDH1A1 (0.54) | CSF1RBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4726486-B2 | — | — | 2011-07-20 | — | — | JP | claimed |