Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13779200 | 0.86 | PDK2 (0.45) | PDK2KIF11HSP90AA1TDP2 | |
| SCHEMBL12295377 | 0.85 | PDK2 (0.45) | PDK2KIF11RAPGEF4NFE2L2 | |
| SCHEMBL16167859 | 0.83 | PDK2 (0.43) | PDK2KIF11HSP90AA1TDP2 | |
| SCHEMBL14330031 | 0.80 | PDK2 (0.43) | PDK2KIF11P2RX1TMPRSS4RAPGEF4 | |
| SCHEMBL12374333 | 0.78 | PDK2 (0.38) | PDK2 | |
| SCHEMBL12937187 | 0.77 | KDM4E (0.46) | PDK2GPR3 | |
| SCHEMBL13326299 | 0.76 | PDK2 (0.45) | PDK2KIF11HSP90AA1TDP2 | |
| SCHEMBL19750291 | 0.75 | PDK2 (0.42) | PDK2KIF11 | |
| SCHEMBL14330042 | 0.75 | PDK2 (0.40) | PDK2 | |
| SCHEMBL19286810 | 0.74 | PDK2 (0.47) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090167170-A1 | Polymer | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-07-02 | — | — | US | disclosed |
| US-20090167170-A1 | Polymer | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-07-02 | — | — | US | disclosed |
| US-7494720-B2 | 9-aryl and bisaryl substituted polyfluorenes | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-02-24 | — | — | US | disclosed |
| US-7494720-B2 | 9-aryl and bisaryl substituted polyfluorenes | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090167170-A1 | Polymer | AHR, PARG, PARN | PDK2 2277/4885KIF11 2246/4885P2RX1 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.