Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13779201 | 0.85 | PDK2 (0.45) | PDK2NFE2L2RAPGEF4KIF11 | |
| SCHEMBL13779200 | 0.82 | PDK2 (0.45) | PDK2KDM1AKIF11 | |
| SCHEMBL25629530 | 0.81 | PDK2 (0.46) | PDK2KIF11MEN1KMT2ATSHR | |
| SCHEMBL16167859 | 0.79 | PDK2 (0.43) | PDK2KDM1AKIF11 | |
| SCHEMBL25473944 | 0.76 | PDK2 (0.47) | PDK2MEN1KMT2ATSHRRAB9A | |
| SCHEMBL19286967 | 0.76 | ACHE (0.48) | PDK2RAPGEF4 | |
| SCHEMBL17666355 | 0.75 | ESR1 (0.47) | PDK2KDM1ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL12374340 | 0.73 | ACHE (0.52) | PDK2KDM1ASLC6A3SLC6A2KMT2A | |
| SCHEMBL14330031 | 0.73 | PDK2 (0.43) | PDK2NFE2L2RAPGEF4KIF11 | |
| SCHEMBL21258346 | 0.73 | NPSR1 (0.48) | PDK2KIF11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2363423-A1 | 9-aryl and bisaryl subtituted polyfluorenes | CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) | 2011-09-07 | — | — | EP | disclosed |
| US-20090167170-A1 | Polymer | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-07-02 | — | — | US | disclosed |
| US-20090167170-A1 | Polymer | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-07-02 | — | — | US | disclosed |
| US-7494720-B2 | 9-aryl and bisaryl substituted polyfluorenes | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-02-24 | — | — | US | disclosed |
| US-7494720-B2 | 9-aryl and bisaryl substituted polyfluorenes | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090167170-A1 | Polymer | AHR, PARG, PARN | PDK2 2277/4885KDM1A 404/4885NFE2L2 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.