Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.74 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.74 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 4/20 | 0.72 |
| ▸ | GLA | P06280 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.72 |
| ▸ | GFER | P55789 | 2/20 | 0.72 |
| ▸ | MMP2 | P08253 | 1/20 | 0.71 |
| ▸ | MMP9 | P14780 | 1/20 | 0.71 |
| ▸ | MMP8 | P22894 | 1/20 | 0.71 |
| ▸ | MMP13 | P45452 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384472 | 0.91 | NR4A2 (0.75) | KMT2AMEN1RXFP1CACNA1BAPBA1 | |
| SCHEMBL29576909 | 0.91 | NR4A2 (0.75) | KMT2AMEN1RXFP1CACNA1BAPBA1 | |
| SCHEMBL27528263 | 0.89 | MEN1 (0.74) | KMT2AMEN1RXFP1CACNA1BAPBA1 | |
| SCHEMBL1663947 | 0.89 | KDM4E (0.63) | KMT2AMEN1RXFP1CACNA1BAPBA1 | |
| SCHEMBL5219768 | 0.88 | NR4A2 (0.83) | KMT2AKDM4EALDH1A1MMP2MMP9 | |
| SCHEMBL20982511 | 0.88 | MMP2 (0.78) | KMT2AKDM4EALDH1A1MMP2MMP9 | |
| Terephthalamide SCHEMBL28143925 | 0.87 | CHEK2 (0.75) | KMT2AMEN1RXFP1CACNA1BAPBA1 | |
| SCHEMBL20982644 | 0.86 | NR4A2 (0.86) | KMT2AKDM4EALDH1A1MMP2MMP9 | |
| SCHEMBL2251258 | 0.86 | MEN1 (1.00) | KMT2AMEN1RXFP1CACNA1BAPBA1 | |
| SCHEMBL14030832 | 0.85 | MMP2 (0.66) | KMT2AKDM4EALDH1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | PRKCH, AIP, PRKCE | KMT2A 2487/4885MEN1 4118/4885RXFP1 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.