Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094649 | 0.80 | KDM4E (0.63) | KDM4EHTTMAPK1LMNAPOLB | |
| SCHEMBL26249047 | 0.76 | ADORA2A (0.34) | KDM4ESLC9A1POLBSMN1; SMN2 | |
| SCHEMBL16117368 | 0.75 | LMNA (0.49) | KDM4ENUDT1MAPK1LMNAPOLB | |
| SCHEMBL3095284 | 0.74 | IKBKB (0.56) | KDM4EHTTPOLBHSD17B10PIK3CB | |
| SCHEMBL10126430 | 0.72 | POLB (0.44) | KDM4ELMNAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL2347424 | 0.72 | KDM4E (0.56) | KDM4EHTTNUDT1SLC9A1MAPK1 | |
| SCHEMBL24710907 | 0.72 | LMNA (0.44) | MAPK1LMNAPIK3CDPIK3CA | |
| SCHEMBL12099918 | 0.70 | IKBKB (0.52) | KDM4EHTTSLC9A1POLBHSD17B10 | |
| SCHEMBL12602972 | 0.69 | CYP3A4 (0.44) | KDM4ENUDT1MAPK1LMNAPOLB | |
| SCHEMBL20154109 | 0.67 | NPSR1 (0.49) | KDM4ENUDT1MAPK1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182140-A1 | Alicyclic Heterocyclic Compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182140-A1 | Alicyclic Heterocyclic Compound | CCR4, CCR1, HRH4 | KDM4E 657/4885HTT 3925/4885NUDT1 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.