Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254637 | 0.84 | CNR1 (0.58) | NPSR1CNR1CTNNB1TCF7L2CNR2 | |
| SCHEMBL7254554 | 0.77 | CNR1 (0.56) | NPSR1CNR1CTNNB1TCF7L2CNR2 | |
| SCHEMBL13780251 | 0.77 | APP (0.63) | HPGDNPSR1CTNNB1TCF7L2LMNA | |
| SCHEMBL4205150 | 0.76 | KMT2A (0.48) | NPC1MAPTRAB9A | |
| SCHEMBL6306174 | 0.74 | HDAC1 (0.57) | HPGDNPSR1LMNAMAPK1NLRP1 | |
| SCHEMBL7254764 | 0.74 | CNR1 (0.57) | CNR1CTNNB1TCF7L2ALDH1A1 | |
| SCHEMBL25251658 | 0.74 | TP53 (0.50) | LMNAMAPK1TP53NPC1MAPT | |
| SCHEMBL7260501 | 0.72 | CTNNB1 (0.65) | CNR1CTNNB1TCF7L2 | |
| SCHEMBL25293955 | 0.71 | HTT (0.51) | HPGDNPSR1LMNAMAPK1TP53 | |
| SCHEMBL13777960 | 0.71 | HPGD (0.46) | HPGDNPSR1CNR1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182140-A1 | Alicyclic Heterocyclic Compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1970373-A1 | ALICYCLIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182140-A1 | Alicyclic Heterocyclic Compound | CCR4, CCR1, HRH4 | HPGD 1929/4885NPSR1 2574/4885CNR1 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.