Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 19/20 | 0.65 |
| ▸ | TCF7L2 | Q9NQB0 | 19/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254637 | 0.87 | CNR1 (0.58) | CTNNB1TCF7L2CNR1 | |
| SCHEMBL7255656 | 0.79 | HRH4 (0.64) | CTNNB1TCF7L2 | |
| SCHEMBL4168559 | 0.79 | CTNNB1 (1.00) | CTNNB1TCF7L2 | |
| SCHEMBL4178349 | 0.79 | CTNNB1 (1.00) | CTNNB1TCF7L2 | |
| SCHEMBL7254554 | 0.78 | CNR1 (0.56) | CTNNB1TCF7L2CNR1 | |
| SCHEMBL7255329 | 0.78 | HRH4 (0.61) | CTNNB1TCF7L2 | |
| SCHEMBL4176748 | 0.77 | CTNNB1 (1.00) | CTNNB1TCF7L2 | |
| SCHEMBL4177162 | 0.77 | CTNNB1 (1.00) | CTNNB1TCF7L2 | |
| SCHEMBL7254764 | 0.75 | CNR1 (0.57) | CTNNB1TCF7L2CNR1 | |
| SCHEMBL7258127 | 0.75 | HRH4 (0.60) | CTNNB1TCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055866-A1 | QUINAZOLINE AND QUINOLINE DERIVATIVE COMPOUNDS AS INHIBITORS OF PROLYLPEPTIDASE, INDUCERS OF APOPTOSIS AND CANCER TREATMENT AGENTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-10 | — | — | WO | disclosed |