SCHEMBL13780428

SCHEMBL13780428

COC1=C/C(=C/C=C2C=C(C)C(=O)C(C)=C2)C=C(C)C1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.62
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
MAPT P10636 3/20 0.45
HKDC1 Q2TB90 2/20 0.45
KDM4E B2RXH2 1/20 0.45
USP2 O75604 1/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALOX5 P09917 3/20 0.38
PTGS2 P35354 2/20 0.38
ALDH1A1 P00352 3/20 0.37
RBBP9 O75884 1/20 0.37
GAA P10253 1/20 0.37
PKM P14618 1/20 0.37
IDO1 P14902 5/20 0.36
CDC25A P30304 2/20 0.36
CDC25B P30305 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13780438 0.98 TYR (0.64) TYRMEN1KMT2AMAPTHKDC1
SCHEMBL13780447 0.96 TYR (0.68) TYRMEN1KMT2AMAPTHKDC1
SCHEMBL13780464 0.85 TYR (0.50) TYRMEN1KMT2AMAPTHKDC1
SCHEMBL13780445 0.85 TYR (0.50) TYRMEN1KMT2AMAPTHKDC1
SCHEMBL13780471 0.85 TYR (0.50) TYRMEN1KMT2AMAPTHKDC1
SCHEMBL361072 0.82 TYR (0.39) TYRMEN1KMT2AMAPTKDM4E
SCHEMBL13780444 0.82 TYR (0.47) TYRALOX5PTGS2
SCHEMBL13780443 0.81 TYR (0.50) TYRMEN1KMT2AMAPTHKDC1
SCHEMBL13780435 0.81 TYR (0.50) TYRMEN1KMT2AMAPTHKDC1
SCHEMBL13780463 0.80 ALOX5 (0.55) TYRALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7560207-B2 Organic photoreceptor and electrophotographic image forming apparatus including the photoreceptor SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-07-14 US disclosed
US-20080014519-A1 Organic photoreceptor and electrophotographic image forming apparatus including the photoreptor SAMSUNG ELECTRONICS CO., LTD. 2008-01-17 US disclosed