Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MPEG1 | Q2M385 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13780470 | 0.95 | ALOX5 (0.44) | ALOX5PTGS2GLS2ACHEBACE1 | |
| SCHEMBL13780453 | 0.95 | ALOX5 (0.46) | ALOX5PTGS2GLS2ACHEBACE1 | |
| SCHEMBL13780448 | 0.93 | ALOX5 (0.42) | ALOX5PTGS2GLS2ACHEBACE1 | |
| SCHEMBL13780461 | 0.87 | ALOX5 (0.38) | ALOX5PTGS2GLS2ACHEBACE1 | |
| SCHEMBL13780462 | 0.86 | ALOX5 (0.36) | ALOX5PTGS2GLS2ACHEBACE1 | |
| SCHEMBL13780455 | 0.86 | — | — | |
| SCHEMBL13780468 | 0.85 | ALOX5 (0.39) | ALOX5PTGS2GLS2ACHEBACE1 | |
| SCHEMBL13780459 | 0.85 | ALOX5 (0.62) | ALOX5PTGS2GLS2MPEG1 | |
| SCHEMBL13780456 | 0.85 | ALOX5 (0.39) | ALOX5PTGS2GLS2ACHEBACE1 | |
| SCHEMBL25814999 | 0.82 | ALOX5 (0.43) | ALOX5PTGS2GLS2ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560207-B2 | Organic photoreceptor and electrophotographic image forming apparatus including the photoreceptor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-07-14 | — | — | US | disclosed |
| US-20080014519-A1 | Organic photoreceptor and electrophotographic image forming apparatus including the photoreptor | SAMSUNG ELECTRONICS CO., LTD. | 2008-01-17 | — | — | US | disclosed |