Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16158151 | 0.88 | GRIN2D (0.50) | MEN1KMT2AALDH1A1CCR6NPSR1 | |
| SCHEMBL16354053 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1CCR6NPSR1 | |
| SCHEMBL7337692 | 0.82 | EPHX2 (0.50) | MEN1KMT2AALDH1A1CCR6NPSR1 | |
| SCHEMBL27414255 | 0.80 | MEN1 (0.44) | MEN1KMT2AALDH1A1CCR6NPSR1 | |
| SCHEMBL3763631 | 0.80 | EPHX2 (0.48) | MEN1KMT2AALDH1A1CCR6NPSR1 | |
| SCHEMBL1323193 | 0.80 | EPHX2 (0.48) | MEN1KMT2AALDH1A1EPHX2GRIN2D | |
| SCHEMBL6858927 | 0.80 | EPHX2 (0.48) | MEN1KMT2AALDH1A1EPHX2GRIN2D | |
| SCHEMBL10835602 | 0.79 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1CCR6NPSR1 | |
| SCHEMBL660423 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1CCR6NPSR1 | |
| SCHEMBL1758641 | 0.78 | EPHX2 (0.50) | MEN1KMT2AALDH1A1CCR6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090169638-A1 | Inhibitors of ribonucleotide reductase subunit 2 and uses thereof | CALANDO PHARMACEUTICALS, INC. (US) | 2009-07-02 | — | — | US | disclosed |