Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85048 | 0.84 | F10 (0.48) | F10DPP4 | |
| SCHEMBL13726768 | 0.84 | F10 (0.58) | F10 | |
| Hydrochloric Acid SCHEMBL77389 | 0.83 | F10 (0.47) | F10DPP4 | |
| SCHEMBL5431953 | 0.77 | F10 (0.52) | F10 | |
| SCHEMBL85844 | 0.77 | F10 (0.47) | F10 | |
| Hydrochloric Acid SCHEMBL77372 | 0.77 | F10 (0.46) | F10 | |
| SCHEMBL5438916 | 0.77 | F10 (0.51) | F10 | |
| SCHEMBL5431950 | 0.77 | F10 (0.51) | F10 | |
| SCHEMBL5438918 | 0.77 | F10 (0.51) | F10 | |
| Hydrochloric Acid SCHEMBL77373 | 0.77 | F10 (0.46) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557222-B2 | 1-[(4-Ethynylphenyl)]-2-[(phenyl)]-pyrrolidine-1,2-dicarboxamide derivatives as inhibitors of coagulation factors Xa and VIIa for the treatment of thrombosis | MERCK PATENT GMBH (DE) | 2009-07-07 | — | — | US | disclosed |
| US-7557222-B2 | 1-[(4-Ethynylphenyl)]-2-[(phenyl)]-pyrrolidine-1,2-dicarboxamide derivatives as inhibitors of coagulation factors Xa and VIIa for the treatment of thrombosis | MERCK PATENT GMBH (DE) | 2009-07-07 | — | — | US | disclosed |
| US-20070093472-A1 | 1-[(4-Ethynylphenyl)]-2-[(phenyl)]-pyrrolidine-1,2-dicarboxamide derivatives as inhibitors of coagulation factors xa and viia for the treatment of thromboses | MERCK PATENT GMBH (DE) | 2007-04-26 | — | — | US | disclosed |
| US-20070093472-A1 | 1-[(4-Ethynylphenyl)]-2-[(phenyl)]-pyrrolidine-1,2-dicarboxamide derivatives as inhibitors of coagulation factors xa and viia for the treatment of thromboses | MERCK PATENT GMBH (DE) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093472-A1 | 1-[(4-Ethynylphenyl)]-2-[(phenyl)]-pyrrolidine-1,2-dicarboxamide derivatives as inhibitors of coagulation factors xa and viia for the treatment of thromboses | F12, F11, F2 | F10 10/4885CTSC 641/4885DPP4 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.