Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345114 | 0.93 | CNR2 (0.40) | PDK2CNR2ALDH1A1SMN1; SMN2GLA | |
| SCHEMBL13780984 | 0.85 | PDK2 (0.40) | PDK2CNR2ALDH1A1SMN1; SMN2GLA | |
| SCHEMBL12116382 | 0.84 | CNR2 (0.43) | PDK2CNR2ALDH1A1SMN1; SMN2GLA | |
| SCHEMBL17692346 | 0.82 | KDM4E (0.38) | PDK2HDAC4KDM4EL3MBTL1ATM | |
| SCHEMBL17692379 | 0.80 | KDM4E (0.36) | PDK2HDAC4KDM4EL3MBTL1ATM | |
| SCHEMBL12865721 | 0.80 | KDM4E (0.38) | PDK2HDAC4KDM4EL3MBTL1ATM | |
| SCHEMBL17691629 | 0.80 | KDM4E (0.36) | PDK2HDAC4RXRARXRBKDM4E | |
| SCHEMBL17692373 | 0.79 | KDM4E (0.35) | PDK2KDM4EL3MBTL1ATM | |
| SCHEMBL17692350 | 0.79 | KDM4E (0.35) | PDK2KDM4EL3MBTL1ATM | |
| SCHEMBL22814606 | 0.79 | KDM4E (0.36) | PDK2ALDH1A1SMN1; SMN2HDAC4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
| WO-2007137725-A1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, OR10J3, PUF60 | PDK2 1068/4885CNR2 4693/4885ALDH1A1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.