Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.39 |
| ▸ | BCHE | P06276 | 8/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13781039 | 0.95 | HDAC6 (0.48) | HDAC6PDK2BCHENOX1MAPT | |
| SCHEMBL24905687 | 0.87 | HDAC6 (0.41) | HDAC6BCHENOX1MAPTLMNA | |
| SCHEMBL13781078 | 0.85 | PDK2 (0.46) | PDK2MAPTLMNAL3MBTL1APEX1 | |
| SCHEMBL21868262 | 0.85 | HDAC6 (0.40) | HDAC6BCHENOX1MAPTLMNA | |
| SCHEMBL21688338 | 0.84 | HDAC6 (0.41) | HDAC6PDK2BCHENOX1L3MBTL1 | |
| SCHEMBL15183545 | 0.84 | HDAC6 (0.41) | HDAC6PDK2BCHENOX1L3MBTL1 | |
| SCHEMBL17929481 | 0.81 | HDAC6 (0.36) | HDAC6BCHENOX1L3MBTL1ACHE | |
| SCHEMBL13781038 | 0.80 | PDK2 (0.41) | PDK2NOX1APEX1 | |
| SCHEMBL14823501 | 0.80 | HDAC6 (0.44) | HDAC6BCHENOX1MAPTLMNA | |
| SCHEMBL12200611 | 0.78 | PDK2 (0.54) | PDK2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, OR10J3, PUF60 | HDAC6 4422/4885PDK2 1068/4885BCHE 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.