Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 15/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15159214 | 0.97 | PDK2 (0.47) | PDK2MEN1KMT2APOLBKDM4E | |
| SCHEMBL13781110 | 0.92 | PDK2 (0.43) | PDK2MEN1KMT2APOLBKDM4E | |
| SCHEMBL13781084 | 0.92 | PDK2 (0.45) | PDK2MEN1KMT2APOLBKDM4E | |
| SCHEMBL12856537 | 0.89 | PDK2 (0.49) | PDK2NPC1HPGDRAB9A | |
| SCHEMBL134303 | 0.89 | PDK2 (0.49) | PDK2NPC1HPGDRAB9A | |
| SCHEMBL26503482 | 0.89 | PDK2 (0.56) | PDK2MEN1KMT2APOLBKDM4E | |
| SCHEMBL13781080 | 0.88 | PDK2 (0.43) | PDK2MEN1KMT2APOLBKDM4E | |
| SCHEMBL14854149 | 0.86 | PDK2 (0.46) | PDK2NPC1HPGDRAB9A | |
| SCHEMBL13781074 | 0.85 | BCL2 (0.41) | PDK2MEN1KMT2AMAPT | |
| SCHEMBL15866674 | 0.84 | MEN1 (0.47) | PDK2MEN1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, OR10J3, PUF60 | PDK2 1068/4885MEN1 405/4885KMT2A 3329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.