Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | STK17B | O94768 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783368 | 0.82 | L3MBTL1 (0.38) | L3MBTL1JAK2JAK1ABL1PDGFRB | |
| SCHEMBL4558848 | 0.81 | L3MBTL1 (0.37) | L3MBTL1JAK2JAK1DRD2LMNA | |
| SCHEMBL13783364 | 0.81 | L3MBTL1 (0.37) | L3MBTL1JAK2JAK1DRD2LMNA | |
| SCHEMBL13783363 | 0.81 | L3MBTL1 (0.37) | L3MBTL1JAK2JAK1ABL1PDGFRB | |
| SCHEMBL13783618 | 0.80 | L3MBTL1 (0.37) | L3MBTL1JAK2JAK1DRD2LMNA | |
| SCHEMBL13783382 | 0.80 | L3MBTL1 (0.37) | L3MBTL1JAK2JAK1DRD2LMNA | |
| SCHEMBL4558219 | 0.80 | L3MBTL1 (0.37) | L3MBTL1JAK2JAK1DRD2LMNA | |
| SCHEMBL13843439 | 0.79 | PRMT5 (0.36) | L3MBTL1JAK2JAK1DRD2LMNA | |
| SCHEMBL13783373 | 0.79 | JAK2 (0.36) | L3MBTL1JAK2JAK1DRD2LMNA | |
| SCHEMBL13783374 | 0.79 | L3MBTL1 (0.34) | L3MBTL1JAK2JAK1DRD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557113-B2 | Substituted pyrrolo[3,2-d]pyrimidine derivatives | TEIJIN PHARMA LIMITED (JP) | 2009-07-07 | — | — | US | disclosed |
| US-7557113-B2 | Substituted pyrrolo[3,2-d]pyrimidine derivatives | TEIJIN PHARMA LIMITED (JP) | 2009-07-07 | — | — | US | disclosed |