Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.80 |
| ▸ | CTSL | P07711 | 17/20 | 0.80 |
| ▸ | CTSS | P25774 | 13/20 | 0.80 |
| ▸ | CTSB | P07858 | 4/20 | 0.80 |
| ▸ | CTSV | O60911 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841396 | 0.95 | CTSK (0.81) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL13784224 | 0.93 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| Relacatib SCHEMBL7258401 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| Relacatib SCHEMBL6841517 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| Relacatib SCHEMBL30218824 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| Relacatib SCHEMBL23856125 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| Relacatib SCHEMBL6215260 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| Relacatib SCHEMBL1587331 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| Relacatib SCHEMBL30218825 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| Relacatib SCHEMBL29394783 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |