Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.52 |
| ▸ | CTSL | P07711 | 18/20 | 0.52 |
| ▸ | CTSS | P25774 | 14/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784250 | 1.00 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4315414 | 0.89 | CTSK (0.49) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4312505 | 0.89 | CTSK (0.49) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4312501 | 0.89 | CTSK (0.49) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4315422 | 0.89 | CTSK (0.49) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6744874 | 0.89 | CTSK (0.54) | CTSKCTSLCTSS | |
| SCHEMBL6744878 | 0.89 | CTSK (0.54) | CTSKCTSLCTSS | |
| SCHEMBL6740606 | 0.87 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6740612 | 0.87 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4312368 | 0.86 | CTSK (0.51) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |