Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587785 | 1.00 | LMNA (0.58) | LMNACYP2D6SPHK1MAPTGMNN | |
| SCHEMBL11410274 | 1.00 | LMNA (0.58) | LMNACYP2D6SPHK1MAPTGMNN | |
| SCHEMBL9887965 | 0.97 | — | — | |
| SCHEMBL29197320 | 0.90 | — | — | |
| SCHEMBL18461275 | 0.88 | LMNA (0.47) | LMNACYP2D6SPHK1MAPTGMNN | |
| SCHEMBL18324135 | 0.84 | TSHR (0.50) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL2507860 | 0.84 | TSHR (0.50) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL17879364 | 0.84 | TSHR (0.50) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL21436918 | 0.84 | TSHR (0.50) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL1333027 | 0.84 | TSHR (0.50) | LMNASPHK1MAPTTSHRGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086547-A1 | ANTIOXIDANT NANOSPHERE COMPRISING [1,2]-DITHIOLANE MOIETIES | CEDARS-SINAI MEDICAL CENTER (US) | 2009-07-09 | — | — | WO | disclosed |