Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 12/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.45 |
| ▸ | NCOR1 | O75376 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | ITGAM | P11215 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17966438 | 0.91 | HRH3 (0.40) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL13784332 | 0.91 | HRH3 (0.40) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17966419 | 0.87 | TSHR (0.39) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL13733473 | 0.87 | TSHR (0.39) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL21563365 | 0.87 | TSHR (0.39) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL29056436 | 0.87 | TSHR (0.39) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL28765920 | 0.87 | TSHR (0.39) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL21831517 | 0.87 | TSHR (0.39) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL21831261 | 0.85 | TSHR (0.41) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL21910159 | 0.85 | TSHR (0.41) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566765-B2 | Heterocyclic compounds containing a nine-membered carbon-nitrogen ring | RIGEL PHARMACEUTICALS, INC. (US) | 2009-07-28 | — | — | US | disclosed |