Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 3/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | NCOR1 | O75376 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17966438 | 1.00 | HRH3 (0.40) | HRH3MLNRPRKCDSMN1; SMN2THRB | |
| SCHEMBL13784334 | 0.91 | HDAC3 (0.45) | HRH3HDAC3NCOR1HDAC4HDAC1 | |
| SCHEMBL29822681 | 0.91 | MLNR (0.38) | HRH3MLNR | |
| SCHEMBL13784337 | 0.89 | SOAT1 (0.43) | HRH3MLNRSMN1; SMN2THRBHPGD | |
| SCHEMBL15762029 | 0.83 | HRH3 (0.40) | HRH3MLNRPRKCDHDAC3NCOR1 | |
| SCHEMBL2672144 | 0.83 | HRH3 (0.40) | HRH3MLNRPRKCDHDAC3NCOR1 | |
| SCHEMBL4402045 | 0.83 | HRH3 (0.40) | HRH3MLNRPRKCDHDAC3NCOR1 | |
| SCHEMBL13399582 | 0.82 | ABCB1 (0.36) | HRH3MLNRPRKCDTHRBHDAC4 | |
| SCHEMBL13290575 | 0.82 | ABCB1 (0.36) | HRH3MLNRPRKCDTHRBHDAC4 | |
| SCHEMBL18751776 | 0.82 | ABCB1 (0.36) | HRH3MLNRPRKCDTHRBHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566765-B2 | Heterocyclic compounds containing a nine-membered carbon-nitrogen ring | RIGEL PHARMACEUTICALS, INC. (US) | 2009-07-28 | — | — | US | disclosed |