Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 15/20 | 0.53 |
| ▸ | AR | P10275 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13366738 | 0.91 | VDR (0.59) | VDRARHDAC3 | |
| SCHEMBL3395070 | 0.85 | VDR (0.60) | VDRARHDAC3 | |
| SCHEMBL3394968 | 0.84 | VDR (0.57) | VDRARHDAC3HDAC6 | |
| SCHEMBL3396474 | 0.82 | VDR (0.59) | VDRARHDAC3HDAC6 | |
| SCHEMBL13366750 | 0.82 | VDR (0.49) | VDRARHDAC3HDAC6 | |
| SCHEMBL3395458 | 0.82 | VDR (0.67) | VDRARHDAC3 | |
| SCHEMBL3395616 | 0.82 | VDR (0.67) | VDRARHDAC3 | |
| SCHEMBL3395933 | 0.81 | VDR (0.58) | VDRARHDAC3 | |
| SCHEMBL13786315 | 0.81 | VDR (0.53) | VDRARHDAC3 | |
| SCHEMBL3389828 | 0.81 | VDR (0.57) | VDRARHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511740-B1 | PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | LILLY CO ELI (US) | 2009-07-08 | — | — | EP | disclosed |