Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | VDR | P11473 | 9/20 | 0.47 |
| ▸ | AR | P10275 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622524 | 0.78 | HDAC6 (0.53) | HDAC6HDAC3HDAC1VDRAR | |
| SCHEMBL3396321 | 0.76 | HDAC6 (0.50) | HDAC6HDAC3HDAC1VDRAR | |
| SCHEMBL14199588 | 0.72 | HDAC6 (0.48) | HDAC6HDAC3HDAC1VDRAR | |
| SCHEMBL6437088 | 0.72 | HDAC6 (0.53) | HDAC6HDAC3HDAC1VDRAR | |
| SCHEMBL3422595 | 0.71 | HDAC6 (0.51) | HDAC6HDAC3HDAC1VDRAR | |
| SCHEMBL13203654 | 0.70 | VDR (0.69) | HDAC6HDAC3HDAC1VDRAR | |
| SCHEMBL13203653 | 0.70 | VDR (0.69) | HDAC6HDAC3HDAC1VDRAR | |
| SCHEMBL2978821 | 0.70 | VDR (0.69) | HDAC6HDAC3HDAC1VDRAR | |
| SCHEMBL13203745 | 0.70 | VDR (0.69) | HDAC6HDAC3HDAC1VDRAR | |
| SCHEMBL2967694 | 0.70 | VDR (0.69) | HDAC6HDAC3HDAC1VDRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511740-B1 | PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | LILLY CO ELI (US) | 2009-07-08 | — | — | EP | disclosed |