Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | VDR | P11473 | 6/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391337 | 0.82 | VDR (0.50) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL3396365 | 0.81 | NPSR1 (0.52) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL13786294 | 0.77 | HDAC3 (0.42) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL3394914 | 0.76 | HDAC6 (0.49) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL3392813 | 0.75 | VDR (0.53) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL3395722 | 0.74 | VDR (0.50) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL3391108 | 0.73 | VDR (0.67) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL13786182 | 0.73 | NPSR1 (0.48) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL3395067 | 0.73 | ESR1 (0.56) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL3394907 | 0.73 | HPGD (0.52) | NPSR1HPGDTSHRMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511740-B1 | PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | LILLY CO ELI (US) | 2009-07-08 | — | — | EP | disclosed |