Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13785988 | 0.87 | HDAC3 (0.31) | HPGDTSHRMAPK1ATMNPSR1 | |
| SCHEMBL13786141 | 0.83 | DAO (0.36) | DAOHPGDTSHRMAPK1ATM | |
| SCHEMBL13786075 | 0.78 | HDAC3 (0.39) | HDAC3HDAC6 | |
| SCHEMBL13786179 | 0.78 | HDAC6 (0.47) | HDAC3HDAC6 | |
| SCHEMBL13786294 | 0.75 | HDAC3 (0.42) | DAOHPGDTSHRMAPK1ATM | |
| SCHEMBL13786250 | 0.74 | DAO (0.38) | DAOHPGDTSHRMAPK1ATM | |
| SCHEMBL13785989 | 0.74 | ESR1 (0.33) | HPGDTSHRMAPK1ATMNPSR1 | |
| SCHEMBL13786182 | 0.73 | NPSR1 (0.48) | HPGDTSHRMAPK1ATMNPSR1 | |
| SCHEMBL3396321 | 0.73 | HDAC6 (0.50) | HDAC3HDAC6 | |
| SCHEMBL13785975 | 0.72 | HDAC3 (0.47) | NPSR1HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511740-B1 | PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | LILLY CO ELI (US) | 2009-07-08 | — | — | EP | disclosed |