Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13785989 | 0.91 | ESR1 (0.33) | HPGDTSHRMAPK1ATMNPSR1 | |
| SCHEMBL13786309 | 0.83 | DAO (0.36) | DAOHPGDTSHRMAPK1ATM | |
| SCHEMBL13786250 | 0.81 | DAO (0.38) | DAOHPGDTSHRMAPK1ATM | |
| SCHEMBL3392513 | 0.72 | HDAC3 (0.38) | DAOHPGDTSHRMAPK1ATM | |
| SCHEMBL13785988 | 0.71 | HDAC3 (0.31) | HPGDTSHRMAPK1ATMNPSR1 | |
| SCHEMBL13366755 | 0.69 | HPGD (0.34) | HPGDTSHRMAPK1ATMNPSR1 | |
| SCHEMBL3390961 | 0.69 | HDAC3 (0.36) | DAOHPGDTSHRMAPK1ATM | |
| SCHEMBL3396321 | 0.69 | HDAC6 (0.50) | — | |
| SCHEMBL13786294 | 0.69 | HDAC3 (0.42) | DAOHPGDTSHRMAPK1ATM | |
| SCHEMBL13366753 | 0.68 | VDR (0.35) | HPGDTSHRMAPK1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511740-B1 | PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | LILLY CO ELI (US) | 2009-07-08 | — | — | EP | disclosed |