Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13250764 | 0.88 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1USP2 | |
| SCHEMBL17850294 | 0.88 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1USP2 | |
| SCHEMBL17850343 | 0.88 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1USP2 | |
| SCHEMBL15592369 | 0.88 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1USP2 | |
| SCHEMBL13447781 | 0.88 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1USP2 | |
| SCHEMBL8651191 | 0.85 | PTPN1 (0.53) | KMT2APOLBALDH1A1USP2MEN1 | |
| SCHEMBL10632505 | 0.85 | PTPN1 (0.53) | KMT2APOLBALDH1A1USP2MEN1 | |
| SCHEMBL26694333 | 0.85 | PTPN1 (0.53) | KMT2APOLBALDH1A1USP2MEN1 | |
| SCHEMBL10632499 | 0.85 | PTPN1 (0.53) | KMT2APOLBALDH1A1USP2MEN1 | |
| SCHEMBL13412970 | 0.85 | LMNA (0.54) | LMNAKMT2APOLBALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089396-A2 | GLYCOCONJUGATION OF POLYPEPTIDES USING OLIGOSACCHARYLTRANSFERASES | NEOSE TECHNOLOGIES, INC. (US) | 2009-07-16 | — | — | WO | disclosed |