Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618603 | 0.84 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL21242212 | 0.73 | TDP1 (0.48) | ALOX5TDP1PLGPLATLMNA | |
| SCHEMBL25486085 | 0.73 | ALOX5 (0.45) | ALOX5OPRM1OPRD1OPRK1 | |
| SCHEMBL3749558 | 0.73 | TDP1 (0.41) | TDP1LMNA | |
| SCHEMBL21582620 | 0.71 | ALOX5 (0.48) | ALOX5TDP1LMNAOPRM1OPRD1 | |
| SCHEMBL15342482 | 0.70 | ALOX5 (0.41) | ALOX5TDP1DDB1CRBNOPRM1 | |
| SCHEMBL29137898 | 0.70 | TDP1 (0.39) | TDP1LMNA | |
| Hydrochloric Acid SCHEMBL5872402 | 0.70 | TDP1 (0.39) | TDP1LMNA | |
| SCHEMBL21224643 | 0.70 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL1627877 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4805909-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| EP-1725522-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2005085185-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-15 | — | — | WO | claimed |