SCHEMBL13789502

SCHEMBL13789502

C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)N1Cc2cc(Cl)c(C(F)(F)F)cc2C1)C(F)(F)F

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 20/20 0.77
SLC6A5 Q9Y345 3/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3870868 0.93 SLC6A9 (0.84) SLC6A9SLC6A5
SCHEMBL1462074 0.90 SLC6A9 (0.75) SLC6A9SLC6A5
SCHEMBL3874059 0.90 SLC6A9 (0.75) SLC6A9SLC6A5
SCHEMBL3916682 0.90 SLC6A9 (0.75) SLC6A9SLC6A5
SCHEMBL4133386 0.90 SLC6A9 (0.78) SLC6A9SLC6A5
SCHEMBL1460953 0.90 SLC6A9 (0.78) SLC6A9SLC6A5
SCHEMBL3872254 0.90 SLC6A9 (0.78) SLC6A9SLC6A5
SCHEMBL3871558 0.89 SLC6A9 (0.77) SLC6A9SLC6A5
SCHEMBL1459956 0.89 SLC6A9 (0.77) SLC6A9SLC6A5
SCHEMBL3934104 0.89 SLC6A9 (0.74) SLC6A9SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7557114-B2 Heterocyclic-substituted phenyl methanones HOFFMAN-LA ROCHE INC. (US) 2009-07-07 US disclosed
US-7557114-B2 Heterocyclic-substituted phenyl methanones HOFFMAN-LA ROCHE INC. (US) 2009-07-07 US disclosed